Large artery stiffening and mortality in a rat model of early vascular remodeling induced by intrauterine growth restriction and a high‐fat diet

Large artery stiffening and mortality in a rat model of early vascular remodeling induced by intrauterine growth restriction and a high‐fat diet

Abstract Intrauterine growth restriction (IUGR) and exposure to a high‐fat diet (HFD) independently increase the risk of cardiovascular disease (CVD) and hyperlipidemia. In our previous studies, IUGR increased blood pressure and promoted vascular remodeling and stiffness in early life, a finding tha...

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Bibliographic Details
Main Authors: Anastasiya Mankouski, Thomas A. Miller, R. Blair Dodson, Baifeng Yu, Yueqin Yang, Jingtong Liu, Daniel R. Machin, Anthony J. Donato, Robert A. McKnight, Erin K. Zinkhan
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Physiological Reports
Subjects:
high fat diet
hypertension
intrauterine growth restriction
vascular remodeling
Online Access:https://doi.org/10.14814/phy2.15518

Internet

https://doi.org/10.14814/phy2.15518

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