Microarray analysis of the in vivo response of microglia to Aβ peptides in mice with conditional deletion of the prostaglandin EP2 receptor

Amyloid-β (Aβ) peptides accumulate in the brains of patients with Alzheimer's disease (AD), where they generate a persistent inflammatory response from microglia, the innate immune cells of the brain. The immune modulatory cyclooxygenase/prostaglandin E2 (COX/PGE2) pathway has been implicated i...

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Bibliographic Details
Main Authors: Jenny U. Johansson, Nathaniel S. Woodling, Holden D. Brown, Qian Wang, Katrin I. Andreasson
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015001208