Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease

Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease

Parkinson disease (PD) is the second most common neurodegenerative disorder, characterized by loss of nigrostriatal dopaminergic neurons. Impairment of the neurovascular unit (NVU) has been hypothesized to play a critical role in early PD pathophysiology, and to precede neurodegenerative mechanisms....

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Bibliographic Details
Main Authors: Jana Ivanidze, Myrto Skafida, Sneha Pandya, Dylon Patel, Joseph R. Osborne, Ashish Raj, Ajay Gupta, Claire Henchcliffe, Jonathan P. Dyke
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neuroscience
Subjects:
molecular imaging
neurovascular unit
PE2I PET
ASL “arterial spin labeling”
Parkinson disease
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.528809/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.528809/full

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