Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin converting enzyme-2/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury

Introduction: Renin–angiotensin system (RAS) components exert diverse physiological functions and have been sub-grouped into deleterious angiotensin-converting enzyme (ACE)/angiotensin II (Ang II)/angiotensin type 1 receptor (AT 1 R) and protective ACE2/angiotensin (1-7) (Ang-(1-7))/Mas receptor (Ma...

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Bibliographic Details
Main Authors: Quaisar Ali, Isha Dhande, Preethi Samuel, Tahir Hussain
Format: Article
Language:English
Published: SAGE Publications 2016-07-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320316661871