Exploring the intricate cross-talk between clonal expansion and the bone marrow niche

Exploring the intricate cross-talk between clonal expansion and the bone marrow niche

Haematopoietic stem cells (HSCs) reside within an intricate network of cells in the bone marrow (BM) niche. HSC crosstalk with niche compartments influences lineage determination and blood cell production, while independent niche interactions are essential for the maintenance of HSC quiescence. How...

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Bibliographic Details
Main Authors: Steven Ngo, Despoina Papazoglou, Hector Huerga Encabo, Dominique Bonnet
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Hematology
Subjects:
bone marrow niche
myeloid leukaemia
clonal haematopoiesis
microenvironment
stromal cells
Online Access:https://www.frontiersin.org/articles/10.3389/frhem.2024.1334807/full

Internet

https://www.frontiersin.org/articles/10.3389/frhem.2024.1334807/full

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