miR-154-5p Is a Novel Endogenous Ligand for TLR7 Inducing Microglial Activation and Neuronal Injury

miR-154-5p Is a Novel Endogenous Ligand for TLR7 Inducing Microglial Activation and Neuronal Injury

Toll-like receptors (TLRs) are a collection of pattern recognition sensors that form a first line of defence by detecting pathogen- or damage-associated molecular patterns and initiating an inflammatory response. TLR activation in microglia, the major immune cells in the brain, can trigger the relea...

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Bibliographic Details
Main Authors: Hugo McGurran, Victor Kumbol, Christina Krüger, Thomas Wallach, Seija Lehnardt
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
microRNA
neurodegeneration
neuroinflammation
toll-like receptor
neurons
microglia
Online Access:https://www.mdpi.com/2073-4409/13/5/407

Internet

https://www.mdpi.com/2073-4409/13/5/407

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