Lymphoblast-derived integration-free ISRM-CON9 iPS cell line from a 75 year old female

Human lymphoblast cells were used to generate integration-free induced pluripotent stem cells (iPSCs) employing episomal-based plasmids expressing OCT4, SOX2, NANOG, LIN28, c-MYC and L-MYC. The derived iPSCs were defined as pluripotent based on (i) expression of pluripotency-associated markers, (ii)...

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Bibliographic Details
Main Authors: Soraia Martins, Martina Bohndorf, Friederike Schröter, Fatima Assar, Wasco Wruck, Kristel Sleegers, Christine Van Broeckhoven, James Adjaye
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302660