Binding of <italic toggle="yes">Candida albicans</italic> to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells

ABSTRACT Candida albicans colonizes human mucosa, including the gastrointestinal tract, as a commensal. In immunocompromised patients, C. albicans can breach the intestinal epithelial barrier and cause fatal invasive infections. Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1; CD6...

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Main Authors: Esther Klaile, Mario M. Müller, Miriam R. Schäfer, Ann-Katrin Clauder, Sabina Feer, Kerstin A. Heyl, Magdalena Stock, Tilman E. Klassert, Peter F. Zipfel, Bernhard B. Singer, Hortense Slevogt
Format: Article
Language:English
Published: American Society for Microbiology 2017-05-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02142-16