Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice.

Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice.

Choroidal neovascularization (CNV) is a defining characteristic feature of neovascular age-related macular degeneration (nAMD) that frequently results in irreversible vision loss. The current strategies for the treatment of nAMD are mainly based on neutralizing vascular endothelial growth factor (VE...

Full description

Bibliographic Details
Main Authors: Sora Im, Jung Woo Han, Euy Jun Park, Ji Hong Bang, Hee Jeong Shin, Hun Soo Chang, Kee Min Woo, Woo Jin Park, Tae Kwann Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0269937

Internet

https://doi.org/10.1371/journal.pone.0269937

Similar Items