Strategies for High-Efficiency Mutation Using the CRISPR/Cas System

Strategies for High-Efficiency Mutation Using the CRISPR/Cas System

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems have revolutionized traditional gene-editing tools and are a significant tool for ameliorating gene defects. Characterized by high target specificity, extraordinary efficiency, and cost-effectiveness, CRISPR/Cas sy...

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Bibliographic Details
Main Authors: Shuying Feng, Zilong Wang, Aifang Li, Xin Xie, Junjie Liu, Shuxuan Li, Yalan Li, Baiyan Wang, Lina Hu, Lianhe Yang, Tao Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CRISPR/Cas system
optimized strategies
highly efficient
mutant
off-target effect
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.803252/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.803252/full

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