Splicing factor SRSF3 represses translation of p21cip1/waf1 mRNA

Abstract Serine/arginine-rich splicing factor 3 (SRSF3) is an RNA binding protein that most often regulates gene expression at the splicing level. Although the role of SRSF3 in mRNA splicing in the nucleus is well known, its splicing-independent role outside of the nucleus is poorly understood. Here...

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Bibliographic Details
Main Authors: Jeeho Kim, Ra Young Park, Younghoon Kee, Sunjoo Jeong, Takbum Ohn
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05371-x