Progesterone Induced Blocking Factor Reduces Hypertension and Placental Mitochondrial Dysfunction in Response to sFlt-1 during Pregnancy

Progesterone Induced Blocking Factor Reduces Hypertension and Placental Mitochondrial Dysfunction in Response to sFlt-1 during Pregnancy

Preeclampsia (PE) is characterized by new onset hypertension in association with placental ischemia, reduced fetal weight, elevated soluble fms-like tyrosine kinase-1 (sFlt-1), and placental mitochondrial (mt) dysfunction and oxidative stress (ROS). Progesterone induced blocking factor (PIBF) is a p...

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Bibliographic Details
Main Authors: Evangeline Deer, Jalisa Jones, Denise C. Cornelius, Kyleigh Comley, Owen Herrock, Nathan Campbell, Sarah Fitzgerald, Tarek Ibrahim, Babbette LaMarca, Lorena M. Amaral
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
hypertension
preeclampsia
sFlt-1
oxidative stress
placental ischemia
Online Access:https://www.mdpi.com/2073-4409/10/11/2817

Internet

https://www.mdpi.com/2073-4409/10/11/2817

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