Targeting LAG-3, TIM-3, and TIGIT for cancer immunotherapy

Abstract In one decade, immunotherapy based on immune checkpoint blockades (ICBs) has become a new pillar of cancer treatment following surgery, radiation, chemotherapy, and targeted therapies. However, not all cancer patients benefit from single or combination therapy with anti-CTLA-4 and anti-PD-1...

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Bibliographic Details
Main Authors: Letong Cai, Yuchen Li, Jiaxiong Tan, Ling Xu, Yangqiu Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-023-01499-1