Praziquantel Reduces Maternal Mortality and Offspring Morbidity by Enhancing Anti-Helminthic Immune Responses

Praziquantel Reduces Maternal Mortality and Offspring Morbidity by Enhancing Anti-Helminthic Immune Responses

Alongside the wide distribution throughout sub Saharan Africa of schistosomiasis, the morbidity associated with this chronic parasitic disease in endemic regions is often coupled with infection-driven immunomodulatory processes which modify inflammatory responses. Early life parasite exposure is the...

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Bibliographic Details
Main Authors: Matthew Lacorcia, Réka Kugyelka, Lorenz Spechtenhauser, Ulrich Fabien Prodjinotho, Youssef Hamway, Thomas Spangenberg, Clarissa Prazeres da Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Schistosomiasis
transgenerational immune priming
Praziquantel (PZQ)
anthelminthic
fetomaternal cross talk
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.878029/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.878029/full

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