Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk

Abstract Genome-wide association studies (GWAS) identify genetic variants associated with a trait, regardless of how those variants are associated with the outcome. Characterizing whether variants for psychiatric outcomes operate via specific versus general pathways provides more informative measure...

Full description

Bibliographic Details
Main Authors: Peter B. Barr, Travis T. Mallard, Sandra Sanchez-Roige, Holly E. Poore, Richard Karlsson Linnér, COGA Collaborators, Irwin D. Waldman, Abraham A. Palmer, K. Paige Harden, Danielle M. Dick
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02171-x