Synthesis, Antimicrobial, and Antibiofilm Activities of Some Novel 7-Methoxyquinoline Derivatives Bearing Sulfonamide Moiety against Urinary Tract Infection-Causing Pathogenic Microbes

Synthesis, Antimicrobial, and Antibiofilm Activities of Some Novel 7-Methoxyquinoline Derivatives Bearing Sulfonamide Moiety against Urinary Tract Infection-Causing Pathogenic Microbes

A new series of 4-((7-methoxyquinolin-4-yl) amino)-<i>N</i>-(substituted) benzenesulfonamide <b>3(a–s)</b> was synthesized via the reaction of 4-chloro-7-methoxyquinoline <b>1</b> with various sulfa drugs. The structural elucidation was verified based on spectrosc...

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Bibliographic Details
Main Authors: Mostafa M. Ghorab, Aiten M. Soliman, Gharieb S. El-Sayyad, Maged S. Abdel-Kader, Ahmed I. El-Batal
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
quinoline
sulfonamide
antimicrobial activity
urinary tract infection
reaction mechanism
Online Access:https://www.mdpi.com/1422-0067/24/10/8933

Internet

https://www.mdpi.com/1422-0067/24/10/8933

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