Loss of Transient Receptor Potential Melastatin 3 ion channel function in natural killer cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients

Loss of Transient Receptor Potential Melastatin 3 ion channel function in natural killer cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients

Abstract Background Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME) is a debilitating disorder that is accompanied by reduced cytotoxic activity in natural killer (NK) cells. NK cells are an essential innate immune cell, responsible for recognising and inducing apoptosis of tumour and...

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Bibliographic Details
Main Authors: Hélène Cabanas, Katsuhiko Muraki, Natalie Eaton, Cassandra Balinas, Donald Staines, Sonya Marshall-Gradisnik
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Molecular Medicine
Subjects:
Transient receptor potential Melastatin 3
Calcium
Chronic fatigue syndrome/Myalgic encephalomyelitis
Natural killer cells
Flow cytometry
Patch-clamp
Online Access:http://link.springer.com/article/10.1186/s10020-018-0046-1

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http://link.springer.com/article/10.1186/s10020-018-0046-1

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