Ursodeoxycholic acid production by Gibberella zeae mutants
Key points Efficient procedures for production and regeneration of Gibberella zeae protoplasts were determined. Fungal mutants were obtained with elevated 7β-hydroxylase activity. Mutant G. zeae M23 almost fully converts LCA (4 g/L) to UDCA.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2022-08-01
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| Series: | AMB Express |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13568-022-01446-2 |