A Comparison of p53 Isoform Profiles and Apoptosis Induced by Camptothecin or a Herbal Khat Extract (<i>Catha Edulis (Vahl) Forssk. ex Endl.</i>) in Leukemic Cell Lines: Exploring Cellular Responses in Therapy Development

A Comparison of p53 Isoform Profiles and Apoptosis Induced by Camptothecin or a Herbal Khat Extract (<i>Catha Edulis (Vahl) Forssk. ex Endl.</i>) in Leukemic Cell Lines: Exploring Cellular Responses in Therapy Development

Khat (<i>Catha edulis (Vahl) Forssk. ex Endl</i>.) is habitually used as a natural stimulant by millions of people, but is associated with adverse effects on gastrointestinal, cardiovascular and central neural systems. At the cellular level khat toxicity involves p53 induction and cell c...

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Bibliographic Details
Main Authors: Therese Bredholt Onyango, Sigrun M. Hjelle, Ingvild Haaland, Olav K. Vintermyr, Anne Christine Johannessen, Bjørn Tore Gjertsen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
p53 isoforms
PTMs
CPT
khat
Online Access:https://www.mdpi.com/2072-6694/12/12/3596

Internet

https://www.mdpi.com/2072-6694/12/12/3596

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