BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke

BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke

Microglial phagocytosis benefits neurological recovery after stroke. Large-conductance Ca2+-activated K+ currents are expressed in activated microglia, and BK channel knockout aggravates cerebral ischemic injury. However, the effect of BK channels on microglial phagocytosis after ischemic stroke rem...

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Bibliographic Details
Main Authors: Shuxian Huang, Tingting Chen, Qian Suo, Rubing Shi, Haroon Khan, Yuanyuan Ma, Yaohui Tang, Guo-Yuan Yang, Zhijun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ischemic stroke
BK channels
microglia
phagocytosis
ERK
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.683769/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.683769/full

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