Biological innovation in the functional landscape of a model regulator, or the lactose operon repressor

The operon model was proposed six decades ago. And yet, despite all this time, the lactose operon repressor, LacI, remains a subject of major interest. While it is well established that LacI can exist in two functional forms, one that renders the operon inactive via binding of LacI to DNA and anothe...

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Bibliographic Details
Main Author: Danchin, Antoine
Format: Article
Language:English
Published: Académie des sciences 2021-07-01
Series:Comptes Rendus Biologies
Subjects:
Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.52/