Systems Toxicology Approach for Assessing Developmental Neurotoxicity in Larval Zebrafish

Adverse outcomes that result from chemical toxicity are rarely caused by dysregulation of individual proteins; rather, they are often caused by system-level perturbations in networks of molecular events. To fully understand the mechanisms of toxicity, it is necessary to recognize the interactions of...

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Bibliographic Details
Main Authors: Roman A. Li, Marja Talikka, Sylvain Gubian, Colette vom Berg, Florian Martin, Manuel C. Peitsch, Julia Hoeng, Anze Zupanic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.652632/full