Adenosine A<sub>2A</sub> Receptor Antagonists Affects NMDA Glutamate Receptor Function. Potential to Address Neurodegeneration in Alzheimer’s Disease

Adenosine A<sub>2A</sub> Receptor Antagonists Affects NMDA Glutamate Receptor Function. Potential to Address Neurodegeneration in Alzheimer’s Disease

(1) Background. <i>N</i>-methyl <span style="font-variant: small-caps;">d</span>-aspartate (NMDA) ionotropic glutamate receptor (NMDAR), which is one of the main targets to combat Alzheimer’s disease (AD), is expressed in both neurons and glial cells. The aim of thi...

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Bibliographic Details
Main Authors: Rafael Franco, Rafael Rivas-Santisteban, Mireia Casanovas, Alejandro Lillo, Carlos A. Saura, Gemma Navarro
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
G-protein-coupled receptors
functional selectivity
microglia
neuroprotection
cognition
signaling
Online Access:https://www.mdpi.com/2073-4409/9/5/1075

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https://www.mdpi.com/2073-4409/9/5/1075

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