Enhancing Acetophenone Tolerance of Anti-Prelog Short-Chain Dehydrogenase/Reductase EbSDR8 Using a Whole-Cell Catalyst by Directed Evolution

The short-chain dehydrogenase/reductase (SDR) from <i>Empedobacter brevis</i> ZJUY-1401 (EbSDR8, GenBank: ALZ42979.1) is a promising biocatalyst for the reduction of acetophenone to (<i>R</i>)-1-phenylethanol, but its industrial application is restricted by its insufficient t...

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Bibliographic Details
Main Authors: Hui Zhang, Bei Wang, Shengli Yang, Hongwei Yu, Lidan Ye
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/12/9/1071