Molecular Rearrangement of Pyrazino[2,3-<i>c</i>]quinolin-5(6<i>H</i>)-ones during Their Reaction with Isocyanic Acid

Molecular Rearrangement of Pyrazino[2,3-<i>c</i>]quinolin-5(6<i>H</i>)-ones during Their Reaction with Isocyanic Acid

New tetrahydropyrazino[2,3-<i>c</i>]quinolin-5(6<i>H</i>)-ones were prepared from 3-chloroquinoline-2,4(1<i>H</i>,3<i>H</i>)-diones and ethylene diamine. In their reaction with HNCO, an unprecedented molecular rearrangement produced new types of hydant...

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Bibliographic Details
Main Authors: Antonín Klásek, Antonín Lyčka, Filip Křemen, Aleš Růžička, Michal Rouchal
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
3-(3-acylureido)-2,3-dihydro-1<i>H</i>-indol-2-ones
4-alkylidene-1’<i>H</i>-spiro[imidazolidine-5,3’-indole]-2,2’-diones
imidazo[1,5-<i>c</i>]quinazoline-3,5-diones
<sup>1</sup>H-, <sup>13</sup>C- and <sup>15</sup>N-NMR
scXRD
biological activity
Online Access:https://www.mdpi.com/1422-0067/23/10/5481

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