CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation.

CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation.

An efficient genome editing approach had been established to construct the stable transgenic cell lines in the domestic chicken (Gallus gallus domesticus) at present. Our objectives were to investigate gene function in the differentiation process of chicken embryonic stem cells (ESCs) into spermatog...

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Bibliographic Details
Main Authors: Yani Zhang, Yingjie Wang, Qisheng Zuo, Dong Li, Wenhui Zhang, Fei Wang, Yanqin Ji, Jing Jin, Zhenyu Lu, Man Wang, Chen Zhang, Bichun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5325261?pdf=render

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http://europepmc.org/articles/PMC5325261?pdf=render

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