Diagnostic and prognostic value of cerebrospinal fluid SNAP-25 and neurogranin in Creutzfeldt-Jakob disease in a clinical setting cohort of rapidly progressive dementias

Diagnostic and prognostic value of cerebrospinal fluid SNAP-25 and neurogranin in Creutzfeldt-Jakob disease in a clinical setting cohort of rapidly progressive dementias

Abstract Background The levels of synaptic markers synaptosomal-associated protein 25 (SNAP-25) and neurogranin (Ng) have been shown to increase early in the cerebrospinal fluid (CSF) of patients with Creutzfeldt-Jakob disease (CJD) and to have prognostic potential. However, no validation studies as...

Full description

Bibliographic Details
Main Authors: Giuseppe Mario Bentivenga, Simone Baiardi, Andrea Mastrangelo, Corrado Zenesini, Angela Mammana, Barbara Polischi, Sabina Capellari, Piero Parchi
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Cognitive Disorders
Dementia
Prion disease
SNAP-25
Neurogranin
Tau
Online Access:https://doi.org/10.1186/s13195-023-01300-y

Internet

https://doi.org/10.1186/s13195-023-01300-y

Similar Items