Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.

Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.

The spindle assembly checkpoint (SAC) monitors microtubule attachment to kinetochores to ensure accurate sister chromatid segregation during mitosis. The SAC members Bub1 and BubR1 are paralogs that underwent significant functional specializations during evolution. We report an in-depth characteriza...

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Bibliographic Details
Main Authors: Claudia Breit, Tanja Bange, Arsen Petrovic, John R Weir, Franziska Müller, Doro Vogt, Andrea Musacchio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144673&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144673&type=printable

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