Transcriptomic landscape based on annotated clinical features reveals PLPP2 involvement in lipid raft-mediated proliferation signature of early-stage lung adenocarcinoma

Transcriptomic landscape based on annotated clinical features reveals PLPP2 involvement in lipid raft-mediated proliferation signature of early-stage lung adenocarcinoma

Abstract Background Image-based screening improves the detection of early-stage lung adenocarcinoma (LUAD)but also highlights the issue of high false-positive diagnoses, which puts patients at a risk of unnecessary over-treatment. Therefore, more precise discrimination criteria are required to ensur...

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Bibliographic Details
Main Authors: Yibei Wang, Ziwei Miao, Xiaoxue Qin, Yi Yang, Si Wu, Qi Miao, Beibei Li, Mingyu Zhang, Pengfei Wu, Yun Han, Bo Li
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Early stage lung adenocarcinoma
Transcriptome sequencing
Lipid rafts
Phospholipid phosphatase 2
Cell proliferation
Online Access:https://doi.org/10.1186/s13046-023-02877-w

Internet

https://doi.org/10.1186/s13046-023-02877-w

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