Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation.

<h4>Background</h4>Tuberculosis (TB) remains a major public health problem globally, even compared to COVID-19. Genome-wide studies have failed to discover genes that explain a large proportion of genetic risk for adult pulmonary TB, and even fewer have examined genetic factors underlyin...

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Bibliographic Details
Main Authors: Michael L McHenry, Jason Simmons, Hyejeong Hong, LaShaunda L Malone, Harriet Mayanja-Kizza, William S Bush, W Henry Boom, Thomas R Hawn, Scott M Williams, Catherine M Stein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010387