Role of Type I Interferons on Filovirus Pathogenesis
Filoviruses, such as Ebola and Marburg virus, encode viral proteins with the ability to counteract the type I interferon (IFN-I) response. These IFN-I antagonist proteins are crucial to ensure virus replication, prevent an antiviral state in infected and bystander cells, and impair the ability of an...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-02-01
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Series: | Vaccines |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-393X/7/1/22 |