The Montreal model: an integrative biomedical-psychedelic approach to ketamine for severe treatment-resistant depression

BackgroundSubanesthetic ketamine has accumulated meta-analytic evidence for rapid antidepressant effects in treatment-resistant depression (TRD), resulting in both excitement and debate. Many unanswered questions surround ketamine’s mechanisms of action and its integration into real-world psychiatri...

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Main Authors: Nicolas Garel, Jessica Drury, Julien Thibault Lévesque, Nathalie Goyette, Alexandre Lehmann, Karl Looper, David Erritzoe, Shannon Dames, Gustavo Turecki, Soham Rej, Stephane Richard-Devantoy, Kyle T. Greenway
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1268832/full