DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference

<p>Abstract</p> <p>Background</p> <p>Inferring molecular pathway activity is an important step towards reducing the complexity of genomic data, understanding the heterogeneity in clinical outcome, and obtaining molecular correlates of cancer imaging traits. Increasingly...

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Bibliographic Details
Main Authors: Purushotham Arnie, Patel Gargi S, Lawler Katherine, Jiao Yan, Jones Annette F, Grigoriadis Anita, Tutt Andrew, Ng Tony, Teschendorff Andrew E
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/403