Alginate‐Laminin Hydrogel Supports Long‐Term Neuronal Activity in 3D Human Induced Pluripotent Stem Cell‐Derived Neuronal Networks

Alginate‐Laminin Hydrogel Supports Long‐Term Neuronal Activity in 3D Human Induced Pluripotent Stem Cell‐Derived Neuronal Networks

Abstract For 3D neural cultures durable hydrogels are required, which persist over a long differentiation period and thus enable the maturation of neuronal networks (NN). Here, 3D models based on human induced pluripotent stem cell‐derived neural progenitor cells that are embedded in hydrogels of ei...

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Bibliographic Details
Main Authors: Julia Hartmann, Ines Lauria, Farina Bendt, Stephan Rütten, Katharina Koch, Andreas Blaeser, Ellen Fritsche
Format: Article
Language:English
Published: Wiley-VCH 2023-02-01
Series:Advanced Materials Interfaces
Subjects:
alginate hydrogel
electrical activity
hiPSC
laminin
long‐term 3D culture
MEA
Online Access:https://doi.org/10.1002/admi.202200580

Internet

https://doi.org/10.1002/admi.202200580

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