Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells

Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells

Reciprocal interactions between prostate epithelial cells and their adjacent stromal microenvironment not only are essential for tissue homeostasis but also play a key role in tumor development and progression. Malignant transformation is associated with the formation of a reactive stroma where canc...

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Bibliographic Details
Main Authors: A. Jaeschke, A. Jacobi, M.G. Lawrence, G.P. Risbridger, M. Frydenberg, E.D. Williams, I. Vela, D.W. Hutmacher, L.J. Bray, A. Taubenberger
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Materials Today Bio
Subjects:
Cancer-associated fibroblasts
Tumor microenvironment
Prostate cancer
Cell mechanics
Atomic force microscopy (AFM)
Real-time deformability cytometry (RT-FDC)
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006420300338

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http://www.sciencedirect.com/science/article/pii/S2590006420300338

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