Construction of a Recombinant Porcine Epidemic Diarrhea Virus Encoding Nanoluciferase for High-Throughput Screening of Natural Antiviral Products

Construction of a Recombinant Porcine Epidemic Diarrhea Virus Encoding Nanoluciferase for High-Throughput Screening of Natural Antiviral Products

Porcine epidemic diarrhea virus (PEDV) is the predominant cause of an acute, highly contagious enteric disease in neonatal piglets. There are currently no approved drugs against PEDV infection. Here, we report the development of a nanoluciferase (NLuc)-based high-throughput screening (HTS) platform...

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Bibliographic Details
Main Authors: Wan Li, Mengjia Zhang, Huijun Zheng, Peng Zhou, Zheng Liu, Anan Jongkaewwattana, Rui Luo, Qigai He
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
PEDV
nanoluciferase
high-throughput screening
antiviral compounds
reverse genetics system
Online Access:https://www.mdpi.com/1999-4915/13/9/1866

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https://www.mdpi.com/1999-4915/13/9/1866

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