Integrated proteomics and metabolomics analysis of sclerosis-related proteins and femoral head necrosis following internal fixation of femoral neck fractures

Integrated proteomics and metabolomics analysis of sclerosis-related proteins and femoral head necrosis following internal fixation of femoral neck fractures

Abstract Femoral head necrosis (FHN) is a serious complication after femoral neck fractures (FNF), often linked to sclerosis around screw paths. Our study aimed to uncover the proteomic and metabolomic underpinnings of FHN and sclerosis using integrated proteomics and metabolomics analyses. We ident...

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Bibliographic Details
Main Authors: Yang Liu, Yongsheng Ma, Wenming Yang, Qitai Lin, Yugang Xing, Huifeng Shao, Pengcui Li, Yong He, Wangping Duan, Xiaochun Wei
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Subjects:
Femoral head necrosis
Proteomics
Metabolomics
Sclerosis around screw paths
Online Access:https://doi.org/10.1038/s41598-024-63837-8

Internet

https://doi.org/10.1038/s41598-024-63837-8

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