USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization

USP14 Positively Modulates Head and Neck Squamous Carcinoma Tumorigenesis and Potentiates Heat Shock Pathway through HSF1 Stabilization

The ubiquitin-proteasome system is a pivotal intracellular proteolysis process in posttranslational modification. It regulates multiple cellular processes. Deubiquitinating enzymes (DUBs) are a stabilizer in proteins associated with tumor growth and metastasis. However, the link between DUBs and HNS...

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Bibliographic Details
Main Authors: Jie Wang, Yuandi Xiang, Zhanghong Xie, Mengqi Fan, Shizhen Fang, Huanzhi Wan, Rui Zhao, Feng Zeng, Qingquan Hua
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
USP14
deubiquitinase
HSF1
HNSCC
oncogene proteins
Online Access:https://www.mdpi.com/2072-6694/15/17/4385

Internet

https://www.mdpi.com/2072-6694/15/17/4385

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