Comprehensive Gene Mutation Profiling of Circulating Tumor DNA in Ovarian Cancer: Its Pathological and Prognostic Impact

Comprehensive Gene Mutation Profiling of Circulating Tumor DNA in Ovarian Cancer: Its Pathological and Prognostic Impact

Liquid biopsies from circulating tumor DNA (ctDNA) have been employed recently as a non-invasive diagnostic tool for detecting cancer-specific gene mutations. Here, we show the comprehensive gene mutation profiles of ctDNA in 51 patients with different histological subtypes of stage I–IV ovarian can...

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Bibliographic Details
Main Authors: Tomoko Noguchi, Naoyuki Iwahashi, Kazuko Sakai, Kaho Matsuda, Hitomi Matsukawa, Saori Toujima, Kazuto Nishio, Kazuhiko Ino
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
circulating tumor DNA (ctDNA)
gene mutation profile
liquid biopsy
ovarian cancer
prognosis
Online Access:https://www.mdpi.com/2072-6694/12/11/3382

Internet

https://www.mdpi.com/2072-6694/12/11/3382

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