MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil

MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil

BackgroundAlthough aging correlates with a worse prognosis for Covid-19, super elderly still unvaccinated individuals presenting mild or no symptoms have been reported worldwide. Most of the reported genetic variants responsible for increased disease susceptibility are associated with immune respons...

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Bibliographic Details
Main Authors: Erick C. Castelli, Mateus V. de Castro, Michel S. Naslavsky, Marilia O. Scliar, Nayane S. B. Silva, Raphaela N. Pereira, Viviane A. O. Ciriaco, Camila F. B. Castro, Celso T. Mendes-Junior, Etiele de S. Silveira, Iuri M. de Oliveira, Eduardo C. Antonio, Gustavo F. Vieira, Diogo Meyer, Kelly Nunes, Larissa R. B. Matos, Monize V. R. Silva, Jaqueline Y. T. Wang, Joyce Esposito, Vivian R. Cória, Jhosiene Y. Magawa, Keity S. Santos, Edecio Cunha-Neto, Jorge Kalil, Raul H. Bortolin, Mário Hiroyuki Hirata, Luiz P. Dell’Aquila, Alvaro Razuk-Filho, Pedro B. Batista-Júnior, Amaro N. Duarte-Neto, Marisa Dolhnikoff, Paulo H. N. Saldiva, Maria Rita Passos-Bueno, Mayana Zatz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
human leukocyte antigens
immune response
major histocompatibility complex (MCH)
HLA
SARS-CoV-2
MUC22
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.975918/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.975918/full

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