Cancer-testis antigen lactate dehydrogenase C4 as a novel biomarker of male infertility and cancer

A unique lactate dehydrogenase (LDH) isoenzyme designated as lactate dehydrogenase C4 (LDH-C4) is found in mammalian mature testis and spermatozoa. Thus far, LDH-C4 has been well studied with regard to its gene and amino acid sequences, structure, biological properties, and peptide synthesis. Accumu...

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Bibliographic Details
Main Authors: Jing Wu, Yan Chen, Yingying Lin, Fenghua Lan, Zhaolei Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.936767/full