Rotavirus NSP4 is secreted from infected cells as an oligomeric lipoprotein and binds to glycosaminoglycans on the surface of non-infected cells

<p>Abstract</p> <p>Background</p> <p>Nonstructural glycoprotein 4 (NSP4) encoded by rotavirus is the only viral protein currently believed to function as an enterotoxin. NSP4 is synthesized as an intracellular transmembrane glycoprotein and as such is essential for viru...

Full description

Bibliographic Details
Main Authors: Didsbury Alicia, Wang Carol, Verdon Daniel, Sewell Mary A, McIntosh Julie D, Taylor John A
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/8/1/551