EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model

EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model

Abstract Background Central post-stroke pain (CPSP) is a chronic and intolerable neuropathic pain syndrome following a cerebral vascular insult, which negatively impacts the quality of life of stroke survivors but currently lacks efficacious treatments. Though its underlying mechanism remains unclea...

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Bibliographic Details
Main Authors: Tongtong Liu, Ting Li, Xuhui Chen, Zuofan Li, Miaomiao Feng, Wenlong Yao, Li Wan, Chuanhan Zhang, Yue Zhang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Neuroinflammation
Subjects:
Central post-stroke pain
Soluble epoxide hydrolase
Endoplasmic reticulum stress
Neuroinflammation
MAPK signaling
Online Access:https://doi.org/10.1186/s12974-021-02255-3

Internet

https://doi.org/10.1186/s12974-021-02255-3

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