Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease

Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease

Abstract: The low incidence of HIV-1 infection in patients with sickle cell disease (SCD) and inhibition of HIV-1 replication in vitro under the conditions of low intracellular iron or heme treatment suggests a potential restriction of HIV-1 infection in SCD. We investigated HIV-1 ex vivo infection...

Full description

Bibliographic Details
Main Authors: Namita Kumari, Tatiana Ammosova, Sharmin Diaz, Xionghao Lin, Xiaomei Niu, Andrey Ivanov, Marina Jerebtsova, Subhash Dhawan, Patricia Oneal, Sergei Nekhai
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920304237

Internet

http://www.sciencedirect.com/science/article/pii/S2473952920304237

Similar Items