Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice

Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice

Alzheimer’s disease (AD) is a destructive and burdensome neurodegenerative disease, one of the most common characteristics of which are neurofibrillary tangles (NFTs) that are composed of abnormal tau protein. Animal studies have suggested that dl-3-n-butylphthalide (dl-NBP) alleviates cognitive imp...

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Bibliographic Details
Main Authors: Yanmin Chang, Yi Yao, Rong Ma, Zemin Wang, Junjie Hu, Yanqing Wu, Xingjun Jiang, Lulu Li, Gang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
Dl-3-n-butylphthalide
tau
P301S
cognitive deficits
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.620176/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.620176/full

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