New Zwitterionic Imidazolones with Enhanced Water Solubility and Bioavailability: Synthesis, Anticancer Activity, and Molecular Docking

New Zwitterionic Imidazolones with Enhanced Water Solubility and Bioavailability: Synthesis, Anticancer Activity, and Molecular Docking

Finding an effective anticancer drug to combat cancer cell resistance remains a challenge. Herein, we synthesized a new series of imidazolone derivatives <b>4a</b>–<b>4i</b> and assessed their anticancer activities against liver cancer cells (Hep3B), Hela cells, and normal LX...

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Bibliographic Details
Main Authors: Saber Abu-Jabal, Ahmad Ghareeb, Derar Smadi, Othman Hamed, Mohyeddin Assali, Avni Berisha, Nael Abutaha, Waseem Mansour, Ameed Omairah, Alaa Janem, Ataa Jaser
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Chemistry
Subjects:
hippuric acid
oxazolone
imidazolones
anticancer
molecular docking
Online Access:https://www.mdpi.com/2624-8549/5/4/169

Internet

https://www.mdpi.com/2624-8549/5/4/169

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