Characterizing Intact IgA2 Antibody and Its Size Variants Using Native Mass Spectrometry and a Tandem MS-based Charge Reduction Approach

Characterizing Intact IgA2 Antibody and Its Size Variants Using Native Mass Spectrometry and a Tandem MS-based Charge Reduction Approach

Characterization of protein structures at multiple levels plays an essential role in study on protein functions. Structural analysis at the intact protein or intact complex level allows access of information on aspects including level of post-translational modification (PTM), distribution of variant...

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Bibliographic Details
Main Author: CHEN Qing-rong;CHAIHU Ling-xiao;CHEN Tao;WANG Guan-bo
Format: Article
Language:English
Published: Editorial Board of Journal of Chinese Mass Spectrometry Society 2022-11-01
Series:Zhipu Xuebao
Subjects:
native mass spectrometry
glycoprotein
protein complex
antibody
iga
size variant
Online Access:http://www.jcmss.com.cn/CN/article/openArticlePDF.jsp?attachType=PDF&id=3107

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http://www.jcmss.com.cn/CN/article/openArticlePDF.jsp?attachType=PDF&id=3107

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