Kinetics study of metaxalone degradation under hydrolytic, oxidative and thermal stress conditions using stability-indicating HPLC method

An isocratic stability indicating RP-HPLCâUV method is presented for the determination of metaxalone (MET) in the presence of its degradation products. The method uses Dr. Maisch C18 column (250 mmÃ4.6 mm, 5 μm) with mobile phase consisting of acetonitrileâpotassium dihydrogen orthophosphate buf...

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Bibliographic Details
Main Authors: Vamsi Krishna Marothu, Rajendra N. Dash, Saritha Vemula, Shravani Donkena, Ramesh Devi, Madhavi Gorrepati
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177912001074