APOE ε4 is associated with disproportionate progressive hippocampal atrophy in AD.

APOE ε4 is associated with disproportionate progressive hippocampal atrophy in AD.

To investigate whether APOE ε4 carriers have higher hippocampal atrophy rates than non-carriers in Alzheimer's disease (AD), mild cognitive impairment (MCI) and controls, and if so, whether higher hippocampal atrophy rates are still observed after adjusting for concurrent whole-brain atrophy ra...

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Bibliographic Details
Main Authors: Emily N Manning, Josephine Barnes, David M Cash, Jonathan W Bartlett, Kelvin K Leung, Sebastien Ourselin, Nick C Fox, Alzheimer's Disease NeuroImaging Initiative
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4039513?pdf=render

Internet

http://europepmc.org/articles/PMC4039513?pdf=render

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