The Effects of Divalent Cation-Chelated Prion Fibrils on the Immune Response of EOC 13.31 Microglia Cells

Transmissible spongiform encephalopathies (TSEs) are epidemic neurodegenerative diseases caused by prion proteins; in particular, they are induced by misfolded prion proteins (PrP<sup>Sc</sup>). PrP<sup>Sc</sup> tend to aggregate into insoluble amyloid prion fibrils (fPrP<...

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Bibliographic Details
Main Authors: Huan-I Jen, Zih-You Lin, Jin-Xun Guo, Cheng-I Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/10/2285